In the late period of pregnancy, calcium mobilization and bone resorption are increased,
and lactation then imposes a further increase [
[1]
]. These changes could lead to osteoporosis and fractures in young women. Pregnancy
and lactation-associated osteoporosis (PLO), first suggested by Nordin and Roper [
[2]
], is a rare form of osteoporosis that occurs in 0.4 per 100,000 women. It is considered
that the number of undiagnosed patients is even higher. PLO leads to multiple fragility
compression fractures in the vertebra. Its exact prevalence, etiology, and pathogenesis
are unknown, and risk factors have not been identified, although heparin use, thyrotoxicosis,
and genetic background have been suspected [
[3]
]. It seems natural that most patients with PLO have associated low bone mineral density
(BMD). However, a case of two vertebral fragility compression fractures with normal
BMD during the postpartum period is presented.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: September 02, 2020
Accepted:
July 21,
2020
Received in revised form:
July 16,
2020
Received:
April 3,
2020
Identification
Copyright
© 2020 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
