Abstract
Background
To investigate muscle volume changes in all body regions after total hip arthroplasty
(THA) with dual-energy X-ray absorptiometry (DEXA), and determine the positive effects
of THA for systemic muscle atrophy in patients with hip osteoarthritis (HOA).
Methods
In total, 116 patients with a mean age of 65.8 (45–84) years who had undergone THA
for unilateral HOA were included in this study. DEXA scans were performed serially
at 2 weeks, 3, 6, 12, 18, and 24 months after THA. The normalized height squared muscle
volume (NMV) and the change ratio of NMV (ΔNMV) were calculated independently for
operated lower extremity (LE), non-operated LE, both upper extremities (UEs), and
trunk. Skeletal mass index, which is a sum of NMV of both LEs and UEs, was evaluated
at 2 weeks and 24 months after THA to identify systemic muscle atrophy equivalent
to the diagnostic criteria of sarcopenia.
Results
ΔNMVs in non-operated LE, both UEs, and trunk increased gradually up to 6, 12, and
24 months after THA, although that in operated LE did not increase during a 24-month
period. The ΔNMVs in operated LE, non-operated LE, both UEs, and trunk at 24 months
after THA were +0.6%, +7.1%, +4.0%, and +4.0%, respectively (P = 0.993, P < 0.001, P < 0.001, P = 0.012). The proportion of systemic muscle atrophy significantly decreased from
2 weeks (38%) to 24 months (23%) after THA (P = 0.022).
Conclusions
THA can potentially have secondary positive effects for systemic muscle atrophy exception
of operated LE.
Keywords
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Article info
Publication history
Published online: March 10, 2023
Accepted:
February 22,
2023
Received in revised form:
February 21,
2023
Received:
October 24,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
